Department of Natural Product Biosynthesis
Max Planck Institute for Chemical Ecology
Hans-Knöll-Straße 8, 07745 Jena, Germany
oconnor (at) ice.mpg.de
Check out Matilde's preprint on how eudicot plants make indole. She discovered a zombie version of the tryptophan beta subunit protein that hijacks the tryptophan biosynthetic pathway. This looks like a universal way to make indole in eudicots.
All 3000 monoterpene indole alkaloids are made by a stereoselective Pictet Spengler reaction that leads to a tetrahydro-beta-carboline...
See Omar and Benke's preprint showing how a single CYP71 can be mutated to lead to 4 monoterpene indole alkaloid scaffolds. They also...
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